Melanin Concentrating Hormone (MCH) (Human, Rat, Mouse)

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Melanin Concentrating Hormone (MCH) (Human, Rat, Mouse) - Antibody for Immunohistochemistry

Catalog#	Standard size	Price	Order
H-070-47	50 µl	$175.00

Image

Slides courtesy Dr. Nae Dun, James H. Quillen College of Medicine
East Tennessee State University

Catalog #

H-070-47

Standard Size

50 µl

Sequence

Asp - Phe - Asp - Met - Leu - Arg - Cys - Met - Leu - Gly - Arg - Val - Tyr - Arg - Pro - Cys - Trp - Gln - Val

Disulfide Bridge: Cys7 - Cys16

Species

Human, Rat, Mouse

Host

Rabbit

Immunogen

Melanin Concentrating Hormone (MCH) (Human, Mouse, Rat)

Reconstitution

For best and reproducible results, reconstitute with 50µl of distilled water for the equivalent of undiluted antiserum, immediately before use. Do not refreeze any unused portions.

Storage Condition

Please store the lyophilized antibody at -20°C upon receipt. For optimal results, use the antibody immediately after reconstitution. Once reconstituted, the antibody is stable for up to three (3) days at 4°C. For longer-term storage up to three (3) months, prepare small aliquots of the reconstituted antibody and freeze at -20°C or -80°C. Repeated freeze-thaw cycles should be strictly avoided.

Content

This vial contains 50µl of Rabbit Anti-MCH (Human, Mouse, Rat) Serum in the lyophilized form.

Recommended Dilution Factor

Immunofluorescence: 1:200
PAP or ABC: 1:500

Cross Reactivity

*Peptide*	*% Cross-reactivity*
Melanin Concentrating Hormone (MCH) (Human, Mouse, Rat)	100
Orexin A (Human, Bovine, Mouse, Rat)	0
Orexin B (Mouse, Rat)	0
AGRP Form C Amide (Human)	0
Leptin (Human)	0
a-MSH	0
NPY (Human, Rat)	0

Alphabet_M_

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this antibody:

E. del Cid-Pellitero, B.E. Jones, Immunohistochemical evidence for synaptic release of GABA from melanin-concentrating hormone containing varicosities in the locus coeruleus.
Neuroscience. 2012 Oct 25;223:269-76. doi: 10.1016/j.neuroscience.2012.07.072. Epub 2012 Aug 10.

Jian-Guo Niu, Shigefumi Yokota, Toshiko Tsumori, Tatsuro Oka, Yukihiko Yasui, Projections from the anterior basomedial and anterior cortical amygdaloid nuclei to melanin-concentrating hormone-containing neurons in the lateral hypothalamus of the rat.
Brain Research, Volume 1479, 15 October 2012, Pages 31-43

Hazai et al. Synaptic alpha-dystrobrevin: localization of a short alpha-dystrobrevin isoform in melanin-concentrating hormone neurons of the hypothalamus.
Brain Res. 2008 Mar 27;1201:52-9.

Glavas et al. Characterization of brainstem peptide YY (PYY) neurons.
J Comp Neurol. 2008 Jan 10;506(2):194-210.

Solomon et al. Peripheral ghrelin interacts with orexin neurons in glucostatic signalling.
Regul Pept. 2007 Dec 4;144(1-3):17-24.

Muschamp et al. Melanin concentrating hormone and estrogen receptor-alpha are coexstensive but not coexpressed in cells of male rat hypothalamus
Neurosci Lett. 2007 Nov 12;427(3):123-6.

Tanabe et al. Functional Single-Nucleotide Polymorphisms in the Secretogranin III (SCG3) Gene that Form Secretory Granules with Appetite-Related Neuropeptides Are Associated with Obesity
J Clin Endocrinol Metab. 2007 Mar;92(3):1145-54.

Kumar et al. Effects of serotonin on perifornical-lateral hypothalamic area neurons in rat
Eur J Neurosci. 2007 Jan;25(1):201-12.

Deurveilher et al. Differential c-Fos immunoreactivity in arousal-promoting cell groups following systemic administration of caffeine in rats.
J Comp Neurol. 2006 Oct 10;498(5):667-89.

Alberto et al. Bidirectional dopaminergic modulation of excitatory synaptic transmission in orexin neurons.
J Neurosci. 2006 Sep 27;26(39):10043-50.

Satoh et al. Expression pattern of FOS in orexin neurons during sleep induced by an adenosine A2A receptor agonist.
Behav Brain Res. 2006 Jun 30;170(2):277-86.

Vidal et al. Hypothalamic and zona incerta neurons expressing hypocretin, but not melanin concentrating hormone, project to the hamster intergeniculate leaflet.
Neuroscience. 2005;134(3):1081-90.

Sun et al. Central and peripheral immunoreactivity of melanin-concentrating hormone in hypothalamic obese and lactating rats.
J Neuroendocrinol. 2004 Jan;16(1):79-83.

Toshinai et al. Ghrelin-Induced Food Intake Is Mediated via the Orexin Pathway
Endocrinology. 2003 Apr;144(4):1506-12.

Zheng et al. Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP
Am J Physiol Regul Integr Comp Physiol. 2002 Jun;282(6):R1773-81.

Lawrence et al. Acute Central Ghrelin and GH Secretagogues Induce Feeding and Activate Brain Appetite Centers
Endocrinology. 2002 Jan;143(1):155-62.

Chiocchio et al. Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels.
Biol Reprod. 2001 May;64(5):1466-72.

Horvath et al. Brain Uncoupling Protein 2: Uncoupled Neuronal Mitochondria Predict Thermal Synapses in Homeostatic Centers
J Neurosci. 1999 Dec 1;19(23):10417-27.