Links to publications that use this kit:
Jeffrey Gagnon and Younes Anini. Insulin and Norepinephrine Regulate Ghrelin Secretion from a Rat Primary Stomach Cell Culture.
Endocrinology. 2012 Aug;153(8):3646-56. doi: 10.1210/en.2012-1040. Epub 2012 Jun 12.
Karin et al., Reduced neurogenesis in the rat hippocampus following high fructose consumption
Regulatory Peptides. doi:10.1016/j.regpep.2010.11.002
Gary K. Yang et al., Involvement of Adenosine Signaling in Controlling the Release of Ghrelin from the Mouse Stomach
JPET January 2011 vol. 336 no. 1 77-86
Anne-Mari Mustonen et al., Response to Fasting in an Unnaturally Obese Carnivore, the Captive European Polecat Mustela putorius
Exp Biol Med November 2009 vol. 234 no. 11 1287-1295
Cummings et al. Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.
Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1782-93.
Aguirre et al. An endoluminal sleeve induces substantial weight loss and normalizes glucose homeostasis in rats with diet-induced obesity.
Obesity (Silver Spring). 2008 Dec;16(12):2585-92.
Erlanson-Albertsson et al. Vagotomy and accompanying pyloroplasty down-regulates ghrelin mRNA but does not affect ghrelin secretion.
Regul Pept. 2008 Nov 29;151(1-3):14-8.
Solomon et al. The effect of feeding frequency on insulin and ghrelin responses in human subjects.
Br J Nutr. 2008 Oct;100(4):810-9.
Lindqvist et al. Effects of sucrose, glucose and fructose on peripheral and central appetite signals.
Regul Pept. 2008 Oct 9;150(1-3):26-32.
Strassburg et al. Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats.
Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E78-84.
Guo et al. Different responses of circulating ghrelin, obestatin levels to fasting, re-feeding and different food compositions, and their local expressions in rats.
Peptides. 2008 Jul;29(7):1247-54.
Carlini et al. Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration
Neuroscience. 2008 Jun 2;153(4):929-34.
Egecioglu et al. Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents.'
Regul Pept. 2008 Feb 7;146(1-3):176-82.
Wang et al. Influence of short- and long-term treadmill exercises on levels of ghrelin, obestatin and NPY in plasma and brain extraction of obese rats.
Endocrine. 2008 Feb;33(1):77-83.
Beck et al. Differential long-term dietary regulation of adipokines, ghrelin, or corticosterone: impact on adiposity.
J Endocrinol. 2008 Jan;196(1):171-9.
Dadan et al. Estimation of gastric ghrelin-positive cells activity in hyperthyroid rats.
Folia Histochem Cytobiol. 2008;46(4):511-7.
Desai et al. Programmed metabolic syndrome: prenatal undernutrition and postweaning overnutrition.
Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2306-14.
Hambly et al. Calorie-restricted mice that gorge show less ability to compensate for reduced energy intake.
Physiol Behav. 2007 Dec 5;92(5):985-92.
de la Cour et al. Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: a microdialysis study.
Regul Pept. 2007 Oct 4;143(1-3):118-26.
Erdmann et al. Plasma ghrelin levels during exercise - effects of intensity and duration.
Regul Pept. 2007 Oct 4;143(1-3):127-35.
Ueno et al. Blunted metabolic response to fasting in obese mice.
Endocrine. 2007 Oct;32(2):192-6.
Martin et al. Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess.
Endocrinology. 2007 Sep;148(9):4318-33.
Seoane et al. Sensory stimuli directly acting at the central nervous system regulate gastric ghrelin secretion. an ex vivo organ culture study.
Endocrinology. 2007 Aug;148(8):3998-4006.
Aprahamian et al. A rat model of childhood diet-induced obesity: Roux-en-Y gastric bypass induced changes in metabolic parameters and gastric peptide ghrelin.
Pediatr Surg Int. 2007 Jul;23(7):653-7.
Ferrer-Lorente et al. Effects of combined oleoyl-estrone and rimonabant on overweight rats.
J Pharmacol Sci. 2007 Jun;104(2):176-82.
Kristensson et al. High gastrin cell activity and low ghrelin cell activity in high-anxiety Wistar Kyoto rats.
J Endocrinol. 2007 May;193(2):245-50.
Fåk et al. Gastric ghrelin cell development is hampered and plasma ghrelin is reduced by delayed weaning in rats.
J Endocrinol. 2007 Feb;192(2):345-52.
Pérez-Tilve et al. Exendin-4 potently decreases ghrelin levels in fasting rats.
Diabetes. 2007 Jan;56(1):143-51.
Wang et al. LPS inhibits fasted plasma ghrelin levels in rats: role of IL-1 and PGs and functional implications.
Am J Physiol Gastrointest Liver Physiol. 2006 Oct;291(4):G611-20.
Gayle et al. Gender-specific orexigenic and anorexigenic mechanisms in rats.
Life Sci. 2006 Sep 13;79(16):1531-6.
Keenan et al. Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat.
Obesity (Silver Spring). 2006 Sep;14(9):1523-34.
Ryökkynen et al. Effects of dietary genistein on mouse reproduction, postnatal development and weight-regulation.
Anim Reprod Sci. 2006 Jul;93(3-4):337-48.
Balasubramaniam et al. Ghrelin stimulates food intake and growth hormone release in rats with thermal injury: synthesis of ghrelin.
Peptides. 2006 Jul;27(7):1624-31.
Mundinger et al. Direct stimulation of ghrelin secretion by sympathetic nerves.
Endocrinology. 2006 Jun;147(6):2893-901.
Kristenssson et al. Acute psychological stress raises plasma ghrelin in the rat.
Regul Pept. 2006 May 15;134(2-3):114-7.
Shearman et al. Ghrelin neutralization by a ribonucleic acid-SPM ameliorates obesity in diet-induced obese mice.
Endocrinology. 2006 Mar;147(3):1517-26.
Drazen et al. Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status.
Endocrinology. 2006 Jan;147(1):23-30.
Otukonyong et al. Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight.
Peptides. 2005 Dec;26(12):2559-66.
Qader et al. Long-term infusion of nutrients (total parenteral nutrition) suppresses circulating ghrelin in food-deprived rats.
Regul Pept. 2005 Nov;131(1-3):82-8.
Archer et al. Hypothalamic energy balance gene responses in the Sprague-Dawley rat to supplementation of high-energy diet with liquid ensure and subsequent transfer to chow.
J Neuroendocrinol. 2005 Nov;17(11):711-9.
Friis-Hansen et al. Reduced ghrelin, islet amyloid polypeptide, and peptide YY expression in the stomach of gastrin-cholecystokinin knockout mice.
Endocrinology. 2005 Oct;146(10):4464-71.
Stefan et al. Hormonal and metabolic defects in a prader-willi syndrome mouse model with neonatal failure to thrive.
Endocrinology. 2005 Oct;146(10):4377-85.
Lindqvist et al. Overeating of palatable food is associated with blunted leptin and ghrelin responses.
Regul Pept. 2005 Sep 15;130(3):123-32.
Proulx et al. Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity.
Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R729-37.
Beck et al. Peptide S is a novel potent inhibitor of voluntary and fast-induced food intake in rats.
Biochem Biophys Res Commun. 2005 Jul 8;332(3):859-65.
Dornonville de la Cour et al. Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice.
Gut. 2005 Jul;54(7):907-13.
Li et al. Ghrelin blunted vascular calcification in vivo and in vitro in rats.
Regul Pept. 2005 Jul 15;129(1-3):167-76.
Stylopoulos et al. Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats.
Surg Endosc. 2005 Jul;19(7):942-6.
Proulx et al. The effect of adrenalectomy on ghrelin secretion and orexigenic action.
J Neuroendocrinol. 2005 Jul;17(7):445-51.
Fernández-Fernández et al. Effects of chronic hyperghrelinemia on puberty onset and pregnancy outcome in the rat.
Endocrinology. 2005 Jul;146(7):3018-25.
Jürgens et al. Consuming fructose-sweetened beverages increases body adiposity in mice.
Obes Res. 2005 Jul;13(7):1146-56.
Drazen et al. Neuropeptide Y prepares rats for scheduled feeding.
Am J Physiol Regul Integr Comp Physiol. 2005 Jun;288(6):R1606-11.
Garcia et al. Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia.
J Clin Endocrinol Metab. 2005 May;90(5):2920-6.
Wettschureck et al. Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.
Mol Cell Biol. 2005 Mar;25(5):1942-8.
Hu et al. Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects.
Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):3972-7.
Korhonen et al. Role of adiposity hormones in the mouse during fasting and winter-acclimatization.
Comp Biochem Physiol A Mol Integr Physiol. 2005 Feb;140(2):217-23.
Tulipano et al. The somatostatin subtype-2 receptor antagonist, BIM-23627, improves the catabolic effects induced by long-term glucocorticoid treatment in the rat.
Regul Pept. 2005 Feb 15;125(1-3):85-92.
Overduin et al. Role of the duodenum and macronutrient type in ghrelin regulation.
Endocrinology. 2005 Feb;146(2):845-50.
Desai et al. Programmed obesity in intrauterine growth-restricted newborns: modulation by newborn nutrition.
Am J Physiol Regul Integr Comp Physiol. 2005 Jan;288(1):R91-6.
Crowley et al. Differential effects of methamphetamine on expression of neuropeptide Y mRNA in hypothalamus and on serum leptin and ghrelin concentrations in ad libitum-fed and schedule-fed rats.
Neuroscience. 2005;132(1):167-73.
Liu et al. Regulation of ghrelin gene expression in stomach and feeding response to a ghrelin analogue in two strains of rats.
Peptides. 2004 Dec;25(12):2171-7.
Beck et al. Feeding response to ghrelin agonist and antagonist in lean and obese Zucker rats.
Life Sci. 2004 Dec 10;76(4):473-8.
Tups et al. Circulating ghrelin levels and central ghrelin receptor expression are elevated in response to food deprivation in a seasonal mammal (Phodopus sungorus).
J Neuroendocrinol. 2004 Nov;16(11):922-8.
Bodosi et al. Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation.
Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1071-9.
Noqueiras et al. Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin.
Diabetes. 2004 Oct;53(10):2552-8.
Gelling et al. Effect of uncontrolled diabetes on plasma ghrelin concentrations and ghrelin-induced feeding.
Endocrinology. 2004 Oct;145(10):4575-82.
Kim et al. Chronic central administration of ghrelin reverses the effects of leptin.
Int J Obes Relat Metab Disord. 2004 Oct;28(10):1264-71.
Vallejo-Cremades et al. Enriched protein diet-modified ghrelin expression and secretion in rats.
Regul Pept. 2004 Sep 15;121(1-3):113-9.
Wu et al. Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis.
Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1296-302.
Chang et al. Ghrelin protects myocardium from isoproterenol-induced injury in rats.
Acta Pharmacol Sin. 2004 Sep;25(9):1131-7.
Ueno et al. Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy.
Endocrinology. 2004 Sep;145(9):4176-84.
Kamegai et al. The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content.
Endocrinology. 2004 Aug;145(8):3731-8.
Wolden-Hanson et al. Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats.
Am J Physiol Regul Integr Comp Physiol. 2004 Jul;287(1):R138-46.
Perreault et al. Resistance to the orexigenic effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss.
Int J Obes Relat Metab Disord. 2004 Jul;28(7):879-85.
Archer et al. Hypothalamic gene expression is altered in underweight but obese juvenile male Sprague-Dawley rats fed a high-energy diet.
J Nutr. 2004 Jun;134(6):1369-74.
Lippl et al. Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach.
Regul Pept. 2004 Jun 15;119(1-2):93-8.
Keen Rhinehart et al. Neuropeptidergic characterization of the leptin receptor mutated obese Koletsky rat.
Regul Pept. 2004 Jun 15;119(1-2):3-10.
Beck et al. Adaptation of ghrelin levels to limit body weight gain in the obese Zucker rat.
Biochem Biophys Res Commun. 2004 Jun 11;318(4):846-51.
Nieminen et al. Reproduction of the tundra vole (Microtus oeconomus) with dietary phytosterol supplement.
Food Chem Toxicol. 2004 Jun;42(6):945-51.
Broglio et al. The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state.
Clin Endocrinol (Oxf). 2004 May;60(5):592-9.
Zhang et al. Inhibition of adipogenesis by ghrelin.
Mol Biol Cell. 2004 May;15(5):2484-91.
Otero et al. Chronic inflammation modulates ghrelin levels in humans and rats.
Rheumatology (Oxford). 2004 Mar;43(3):306-10.
Sun et al. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4679-84.
Kappeler et al. Delayed age-associated decrease in growth hormone pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat.
Neuroendocrinology. 2004;80(5):273-83.
Ishii et al. Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis.
Neuroendocrinology. 2003 Dec;78(6):321-30.
Levin et al. Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats.
Am J Physiol Endocrinol Metab. 2003 Nov;285(5):E949-57.
Chang et al. Therapeutic effects of ghrelin on endotoxic shock in rats.
Eur J Pharmacol. 2003 Jul 25;473(2-3):171-6.
Basa et al. Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats.
Neurosci Lett. 2003 May 29;343(1):25-8.
Caminos et al. Expression of ghrelin in the cyclic and pregnant rat ovary.
Endocrinology. 2003 Apr;144(4):1594-602.
Bagnasco et al. Evidence for the existence of distinct central appetite, energy expenditure, and ghrelin stimulation pathways as revealed by hypothalamic site-specific leptin gene therapy.
Endocrinology. 2002 Nov;143(11):4409-21.
McCowen et al. Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents.
J Endocrinol. 2002 Nov;175(2):R7-11.
Tschöp et al. Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats.
Obes Res. 2002 Oct;10(10):991-9.
Beretta et al. Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes.
Pediatr Res. 2002 Aug;52(2):189-98.
Galas et al. Immunohistochemical localization and biochemical characterization of ghrelin in the brain and stomach of the frog Rana esculenta.
J Comp Neurol. 2002 Aug 12;450(1):34-44.
Gualillo et al. Effect of food restriction on ghrelin in normal-cycling female rats and in pregnancy.
Obes Res. 2002 Jul;10(7):682-7.
Caminos et al. Influence of thyroid status and growth hormone deficiency on ghrelin.
Eur J Endocrinol. 2002 Jul;147(1):159-63.
Beck et al. Ghrelin, macronutrient intake and dietary preferences in long-evans rats.
Biochem Biophys Res Commun. 2002 Apr 12;292(4):1031-5.
Tolle et al. Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats.
Endocrinology. 2002 Apr;143(4):1353-61.
Liu et al. Ghrelin gene expression is age-dependent and influenced by gender and the level of circulating IGF-I.
Mol Cell Endocrinol. 2002 Mar 28;189(1-2):97-103.
Wisse et al. Reversal of cancer anorexia by blockade of central melanocortin receptors in rats.
Endocrinology. 2001 Aug;142(8):3292-301.
Caminos JE. - Endocrinology - Apr 2003; 144: 1594 - 1602/ Andreis PG et al. FEBS LETTERS 536 (2003) 173-179 / Beck - Biochem. & Biophys. Res - Communications 292 - 1031-1035 (2002) / in serum: Wisse B. - Endocrinology - Vol. 42 - No. 8 - pg 3292-3301
