CART, Research Abstracts, Photomicrographs & Sequences

Cocaine and Amphetamine-Regulated Transcript (CART) Protein Precursor Schematic (Human)

CART Preprohormone Schematic (Rat)

Prepro-CART Sequence (Rat)

Catalog #	003-61
Standard Size	100 µg
Sequence	Lys - Tyr - Gly - Gln - Val - Pro - Met - Cys - Asp - Ala - Gly - Glu - Gln - Cys - Ala - Val - Arg - Lys - Gly - Ala - Arg - Ile - Gly - Lys - Leu - Cys - Asp - Cys - Pro - Arg - Gly - Thr - Ser - Cys - Asn - Ser - Phe - Leu - Leu - Lys - Cys - Leu [Disulfide bridges between Cys8&Cys26,Cys14&Cys34 and Cys28&Cys41]
Species	Human, Rat, Mouse
M.W	4513.34
Mass Spec Analysis	Exhibits correct M.W.
Solubility	Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition	Store peptide in DRY form at 0-5°C.
Appearance	White powder
Content	The contents of this vial have been accurately determined to contain 100µg of NET peptide.
HPLC Analysis	Purity: Single band on 15% Tricine-PAGE gel.
Additional articles	For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this peptide:

Bewick et al. Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release.
Endocrinology. 2005 Aug;146(8):3526-34.

Stanley et al. Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids
Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E583-90.

Hwang et al. Central pressor effects of CART peptides in anesthetized rats.
Neuropeptides. 2004 Apr-Jun;38(2-3):69-76.

For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions.