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Insulin-like 3 (INSL3) (Human) RIA Kit Data Sheet

Cat. No.: RK-035-27


Sensitivity:

IC50: 5.2 -10.5 pg /100 ul ( 52-105 pg/ml )

Linear range:

3~32 pg/100 ul ( 30~ 320 pg/ml )
Standard Range: 1-128 pg/100 ul (10-1280 pg/ml)

 

 


Measurement of  human Insulin-like 3 immunoreactivity (non-extracted serum and
plasma samples) in healthy subjects
 
  Male
(Mean ± SD, n=8)		 Female
(Mean ± SD, n=8)
Serum 758.42±83.21
pg/ml		 59.42 ±25.76
pg/ml
Plasma 594.10±118.7
pg/ml 		 47.13±19.84
pg/ml
 

 

 

 

 

 

 

 


Specificity

 
Peptide % Crossreactivity
Insulin Like 3 (INSL3) (Human)
100
INSL 4 (Human)
0
INSL5 (Mouse)
0
  INSL6 (Human)
0
INSL7 (Human)
0
Insulin (Human)
0
C-peptide (Human)
0
  Amylin (Human)
0
  Glucagon (Human)
0
 

 



References:

1. Ferlin A, Garolla A, Rigon F, Caldogno LR, Lenzi A, Foresta C. Changes in serum Insulin-like factor 3 (INSL3) during normal male puberty. J Clin Endocrinol Metab. 2006 Jun 27; [Epub ahead of print];

2. Klonisch T, Muller-Huesmann H, Riedel M, Kehlen A, Bialek J, Radestock Y, Holzhausen HJ, Steger K, Ludwig M, Weidner W, Hoang-Vu C, Hombach-Klonisch S. INSL3 in the benign hyperplastic and neoplastic human prostate gland. Int J Oncol. 2005 Aug;27(2):307-15

3.Ferlin A, Foresta C. Insulin-like factor 3: a novel circulating hormone of testicular origin in humans. Ann N Y Acad Sci. 2005 May;1041:497-505.