Visualization of Receptor Dynamic Trafficking in Living Cells
Fluorescent Peptides as potent receptor ligands, in conjunction with confocal microscopy, enable to
study the dynamic relationship between receptor internalization,
desensitization, down-regulation by monitoring the trafficking of these Fluorescent
Peptide Ligands in living cells.
1. Arttamangkul S., et al. Binding and Internalization of Fluorescent
Opioid Peptide Conjugates in Living Cells. Mol Pharmacol. 2000
Dec;58(6):1570-1580
2. Beaudet A., et al. Fluorescent ligands for studying neuropeptide
receptors by confocal microscopy. Braz J Med Biol Res. 1998 Nov;31(11):1479-89.
3. Fabry M., et al. Monitoring of the internalization of neuropeptide Y on
neuroblastoma cell line SK-N-MC. Eur J Biochem 2000 Sep;267(17):5631-7
Custom Labeling
Besides the wide selection of fluorescent peptides we offer in our catalog,
we can custom label any peptide you need. Please contact us for more information
on any tracer of your interest, or click here to request a quotation on your custom needs.
Detection of Peptide Receptors in the tissue slide with Fluorescent-Peptide:
Dagar S.. et al. Detection of VIP receptors in MNU-induced breast cancer in
rats: implications for breast cancer targeting. Breast Cancer Res. Treat. 65(1):49-54, 2001
Monitoring Fluorescent peptide binding sites
in plasma membrane with flow cytometry [More
info]
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