Orphanin FQ {Nociceptin} Prohormone Schematic (Human)

Nociceptin Sequence Comparison

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	EK-021-55
Standard Size	96 wells
Sensitivity	Minimum Detectable Concentration = 0.18 ng/ml
Range	0-100ng/ml
Linear Range	0.18-1.76 ng/ml
Cross Reactivity	Peptide   %Cross-reactivity  Orphanin FQ (OFQ)  100  Met-Enkephalin  0  Dynorphin A  0  b-Endorphin (Human)  0
Sequence	Phe - Gly - Gly - Phe - Thr - Gly - Ala - Arg - Lys - Ser - Ala - Arg - Lys - Leu - Ala - Asn - Gln
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Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Guo et al. Acute myocardial ischemia up-regulates nociceptin/orphanin FQ in dorsal root ganglion and spinal cord of rats.
Neurosci Lett. 2008 Mar 15;433(3):274-8.

Miller et al. Regulation of nociceptin/orphaninFQ secretion by immune cells and functional modulation of interleukin-2
Peptides. 2007 Nov;28(11):2243-52.

Takayama et al. Morphine-induced overexpression of prepro-nociceptin/orphanin FQ in cultured astrocytes.
Peptides. 2005 Dec;26(12):2513-7.

Naito et al. Application of an Enzyme Immunoassay for Nociceptin (Orphanin FQ)-like Immunoreactive Substances to Determination of the Human Plasma Levels
J. Health Science, Vol. 49(5), pp 353-358, 2003