Endothelin and Endothelin-like Peptides

Preproendothelin-1: Placenta, Lung, Umbillical Vein (Human)

Endothelin-1 Precursor (ET-1) Sequence

Preproendothelin-1 (Porcine)

Normal Plasma Peptide/Protein Levels

Protocol	Assay Protocol (PDF)
Sample Preparation	Blood collection Plasma extraction Tissue extraction CSF extraction
Catalog #	EK-023-01
Standard Size	96 wells
Sensitivity	Minimum Detectable Concentration = 0.13ng/ml
Range	0-25 ng/ml
Linear Range	0.13-1.72ng/ml
Cross Reactivity	Peptide % Cross-reactivity Endothelin-1 (Human, Porcine, Rat, Mouse, Canine, Bovine, Rabbit, Monkey) 100 Endothelin-2 (Human, Porcine, Rat, Mouse, Canine, Bovine)  100 Endothelin-3 (Human, Porcine, Rat, Mouse, Canine, Bovine) 100 Big Endothelin-1 (Human) 16 Big Endothelin-2 (Human) 7 Angiotensin II (Human) 0 [Arg8]-Vasopressin 0
Sequence	Cys - Ser - Cys - Ser - Ser - Leu - Met - Asp - Lys - Glu - Cys - Val - Tyr - Phe - Cys - His - Leu - Asp - Ile - Ile - Trp Disulfide Bridge: Cys1 - Cys15 and Cys3 - Cys11
Standard Curve Image

Please click here or click the reference tab on the top to see more articles that use this product.

Links to publications that use this kit:

Schellenberg et al. Analytical validation of commercial immunoassays for the measurement of cardiovascular peptides in the dog.
Vet J. 2008 Oct;178(1):85-90.

Karaoglan et al. The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats
Surg Neurol. 2008 Oct;70(4):337-43.

Zhan et al. Dietary arginine supplementation affects microvascular development in the small intestine of early-weaned pigs.
J Nutr. 2008 Jul;138(7):1304-9.

Liou et al. The vasorelaxing action of labedipinedilol-A involves endothelial cell-derived NO and eNOS expression caused by calcium influx.
J Cardiovasc Pharmacol. 2005 Mar;45(3):232-40.

Aydin et al. Plasma malondialdehyde, superoxide dismutase, sE-selectin,fibronectin, endothelin-1 and nitric oxide levels in women with preeclampsia
Eur J Obstet Gynecol Reprod Biol. 2004 Mar 15;113(1):21-5.

Karter et al. Endothelium and angiogenesis in white coat hypertension
J Hum Hypertens. 2004 Nov;18(11):809-14.