中文网站正在持续更新中,请密切关注我们康肽生物的最新动态,或点击访问右上角的英文官方网站 www.phoenixpeptide.com
PHOENIX PHARMACEUTICALS, INC. TOP HOME PAGE
Top Catalog English Version | My Account | 联系我们 | China



 多肽



 标记多肽 



 多肽激素文库



 抗体 



 免疫试剂盒 



 生物标志物阵列 



 多肽样品检测



 自定义肽链合成及GMP



 产品目录索取



 样品准备



 提问和解答


WKYMVM

An agonist for the orphan receptor chemoattractant receptor FPRL1 and FPRL2.

Different chemoattractants induce leukocyte infiltration and activation through binding to G protein-coupled receptor. FPRL1, and FPRL2 belong to the N-formyl peptide chemoattractant G protein-coupled receptor family (FPR). Two synthetic hexapeptides Trp-Lys-Tyr-Met-Val-Met-NH2 (WKYMVM) and Trp-Lys-Tyr-Met-Val-D-Met-NH2 (WKYMVm) specifically bind to FPRL1 and FPRL2.

Its L or D conformers also induce phosphorylation and internalization of FPRL1. The data indicated that neutrophils are activated by WKYMVM through FPRL1 and FPRL2 is a chemotactic receptor transducing signals in myeloid cells.

Christophe, T. et al. J. Biol. Chem. online April 02, 2001

Related Chemotactic Peptide Products

Want to visualize FPRL1 and FPRL2 dynamic trafficking in living cells?

Try fluorescent WKYMVM / WKYMVm !!!

Ac2-26 is a ligand for Formylated Peptide Recepto

Monitoring Formylated Peptide Receptor with Fluorescent Peptide

 

072-01;072-03;072-04;072-05;072-06;072-07;072-08;072-09;072-11;072-12;072-16;072-17;072-20


分类搜索
关键字搜索
按字母搜索
A B C D E F G H I J K L M N
O P Q R S T U V W X Y Z

Copyright 2020 PHOENIX BIOTECH